Description

5-Bromo-2-Chloroquinazoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, the bromine and chlorine substituents, which enable selective cross-coupling reactions and further functionalization. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	5-Bromo-2-Chloroquinazoline
CAS No.	134517-33-2
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	2-Chloro-5-bromoquinazoline; 5-Bromo-2-chloro-quinazoline; Quinazoline, 5-bromo-2-chloro-; 134517-33-2; 5-Bromo-2-chloroquinazoline; 2-Chloro-5-bromo-quinazoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloroquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.