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Fluoranthene-3-14C CAS NO 134459-04-4
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CAS No.:134459-04-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Fluoranthene-3-14C is a carbon-14 radiolabeled derivative of the polycyclic aromatic hydrocarbon (PAH) fluoranthene, specifically labeled at the 3-position. This compound is an essential tool for advanced environmental fate, metabolic, and pharmacokinetic studies, providing a reliable radioactive tracer for precise analytical detection. It is primarily required by research institutions, environmental testing laboratories, and pharmaceutical R&D departments engaged in sophisticated analytical chemistry and toxicology research.
Application
- Environmental Fate and Metabolism Studies: Used as a radiolabeled tracer to investigate the degradation, transformation, and bioaccumulation of PAHs in soil, water, and biological systems.
- Pharmacokinetic and ADME Research: Enables the detailed tracking of absorption, distribution, metabolism, and excretion (ADME) profiles of fluoranthene and related compounds in preclinical models.
- Analytical Method Development: Serves as a critical internal standard or reference material in the development and validation of sensitive analytical methods like LC-MS/MS or radio-HPLC.
- Toxicological Research: Facilitates studies on the mechanisms of PAH toxicity, including DNA adduct formation and metabolic activation pathways.
- Biodegradation and Remediation Research: Used to monitor and quantify the efficiency of microbial or chemical remediation processes targeting PAH contaminants.
Basic Information
| Product Name | Fluoranthene-3-14C |
| CAS No. | 134459-04-4 |
| Molecular Formula | C16H10 (with 14C at position 3) |
| Molecular Weight | ~202.26 g/mol (exact mass depends on 14C enrichment) |
| Synonyms | 3-14C-Fluoranthene; [3-14C]Fluoranthene; Fluoranthene (3-14C); 1,2-(1,8-Naphthylene)benzene-3-14C; Benzo[jk]fluorene-3-14C; Idryl-3-14C; Radioactive Fluoranthene; 14C-Labelled Fluoranthene |
| EINECS | Contact for details |
Quality Control
Every batch of Fluoranthene-3-14C is produced and controlled to meet the stringent requirements for radiochemical purity and specific activity demanded by research applications. Quality is assured through comprehensive analytical techniques including radio-HPLC and liquid scintillation counting (LSC). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting specific activity, radiochemical purity, chemical purity, and solvent information.
Storage
Preserve in a tightly closed container, protected from light. Store the solution at the recommended temperature (typically 2-8°C or as specified on the label) in an area designated for radioactive materials. Follow all local and international regulations for the safe handling and storage of radioactive compounds.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear solution (color may vary) |
| Identification (HPLC) | Conforms to reference standard |
| Specific Activity | 50-60 mCi/mmol (Contact for exact value) |
| Radiochemical Purity (Radiometric HPLC) | ≥ 97% |
| Chemical Purity (HPLC) | ≥ 95% |
| Concentration | 0.1 mCi/mL in toluene (or as specified) |
| Solvent | Toluene (or as specified on COA) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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