Description

(2R,4R,6R,10S,12R,13R)-10,13-Bis(Acetyloxy)-4,15-Dimethyl-12-(1-Methylethenyl)-3,7,17-Trioxatetracyclo[12.2.1.16,9.02,4]Octadeca-9(18),14,16(1)-Trien-8-One is a complex, high-purity diterpenoid derivative with a defined stereochemistry. This compound is valued for its role as a critical advanced pharmaceutical intermediate and a versatile scaffold in organic synthesis. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors developing novel therapeutic agents and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel diterpene-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Natural Product Synthesis: Serves as a pivotal intermediate in the total or semi-synthesis of complex natural products with biological activity.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for the production of high-value specialty chemicals.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2R,4R,6R,10S,12R,13R)-10,13-Bis(Acetyloxy)-4,15-Dimethyl-12-(1-Methylethenyl)-3,7,17-Trioxatetracyclo[12.2.1.16,9.02,4]Octadeca-9(18),14,16(1)-Trien-8-One
CAS No.	134455-94-0
Molecular Formula	C24H30O8
Molecular Weight	446.49 g/mol
Synonyms	Taxinine M; 2-Deacetyltaxinine M; 10-Deacetyl-7,10-dideoxytaxusin; (1S,2S,5R,7S,10S,11S,12S)-5,12-Diacetoxy-1,8-dimethyl-11-(prop-1-en-2-yl)-4,14,17-trioxatetracyclo[11.2.1.15,8.02,11]heptadeca-8,15-dien-13-one; 10-Deacetyl-7,10-dideoxytaxinine M; 2-Deacetyl-10-deacetyltaxinine M; 7,10-Dideoxytaxinine M
EINECS	Contact for details

Quality Control

Our (2R,4R,6R,10S,12R,13R)-10,13-Bis(Acetyloxy)-4,15-Dimethyl-12-(1-Methylethenyl)-3,7,17-Trioxatetracyclo[12.2.1.16,9.02,4]Octadeca-9(18),14,16(1)-Trien-8-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistent quality and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.