Description

Allyl Ribofuranoside is a versatile nucleoside derivative where an allyl group is attached to the ribofuranose sugar moiety. This compound serves as a crucial building block in organic synthesis, particularly for the preparation of modified nucleosides and nucleotides. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Bioconjugation Chemistry: The allyl group enables further functionalization via click chemistry (e.g., thiol-ene reactions) for labeling or attaching biomolecules.
• Oligonucleotide Synthesis: Used in the research and development of modified RNA and DNA strands with tailored properties.
• Glycosylation Studies: Acts as a glycosyl donor or acceptor in enzymatic and chemical glycosylation reactions to study carbohydrate interactions.
• Prodrug Development: Incorporated into prodrug strategies to enhance the bioavailability or targeting of therapeutic agents.
• Chemical Biology Probes: Serves as a scaffold for creating probes to investigate enzymatic mechanisms and cellular pathways.

Basic Information

Product Name	Allyl Ribofuranoside
CAS No.	134149-47-6
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	1-O-Allyl-β-D-ribofuranose; Allyl β-D-ribofuranoside; 1-O-Allyl-β-D-ribose; β-D-Ribofuranose, 1-O-2-propen-1-yl-; Allyl D-ribofuranoside; 1-Allyl-β-D-ribofuranose; 2-Propen-1-yl β-D-ribofuranoside
EINECS	Contact for details

Quality Control

Our Allyl Ribofuranoside is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.