Description

(1S,2S)-(+)-2-Methoxycyclohexanol is a chiral, non-racemic compound featuring a methoxy-substituted cyclohexanol backbone. This specific stereoisomer is highly valued as a versatile chiral building block and intermediate in asymmetric synthesis. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, enantiomerically enriched intermediates for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereochemistry can be critical for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis, such as hydrogenation and epoxidation reactions.
• Fine Chemical and Flavor/Fragrance Intermediate: Employed in the synthesis of complex, high-value aroma chemicals and specialty fine chemicals requiring defined stereochemistry.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for studying stereoselective reaction pathways.
• Material Science: Potential use as a monomer or modifying agent for creating chiral polymers and advanced functional materials with specific optical properties.

Basic Information

Product Name	(1S,2S)-(+)-2-Methoxycyclohexanol
CAS No.	134108-92-2
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	(1S,2S)-2-Methoxycyclohexanol; (+)-(1S,2S)-2-Methoxycyclohexanol; trans-(+)-2-Methoxycyclohexanol; (1S,2S)-rel-2-Methoxycyclohexanol; Cyclohexanol, 2-methoxy-, (1S,2S)-; (1S,2S)-(+)-2-Methoxy-1-cyclohexanol
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-2-Methoxycyclohexanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]D20	+20° to +25° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.