Description

(S)-4-Carboxyphenylglycine CAS NO 134052-73-6 is a high-purity, non-proteinogenic amino acid derivative characterized by its chiral (S)-configuration and a carboxylic acid functional group on the phenyl ring. This compound serves as a critical chiral building block and intermediate in the synthesis of advanced pharmaceuticals and bioactive molecules. It is essential for research and production in the pharmaceutical industry, particularly for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, including enzyme inhibitors and receptor antagonists.
• Peptide Mimetics & Drug Design: Used to incorporate constrained, aromatic amino acid motifs into peptide backbones to enhance stability and biological activity.
• Chemical Biology Research: Employed as a tool compound for studying enzyme mechanisms and protein-ligand interactions.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands used in asymmetric synthesis and catalysis.
• Agrochemical Research: Potential intermediate in the development of novel, chiral active ingredients for crop protection.
• Diagnostic Reagent Development: Can be utilized in the creation of specialized reagents and probes for biochemical assays.

Basic Information

Product Name	(S)-4-Carboxyphenylglycine
CAS No.	134052-73-6
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	(S)-2-Amino-2-(4-carboxyphenyl)acetic acid; (S)-4-Carboxy-DL-phenylglycine; (S)-α-Amino-4-carboxybenzeneacetic acid; (S)-4-Carboxyphenylglycine; L-4-Carboxyphenylglycine; (S)-Amino(4-carboxyphenyl)acetic acid; 4-Carboxy-(S)-phenylglycine; 4-Carboxy-L-phenylglycine
EINECS	Contact for details

Quality Control

Our (S)-4-Carboxyphenylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.