Description

2-Azabicyclo[2.2.1]Heptan-3-One, (1R,4S)- is a high-purity, chiral bicyclic lactam building block of significant synthetic utility. Its rigid, constrained structure makes it a valuable intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the creation of advanced, stereochemically-defined pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand framework in the development of chiral catalysts for enantioselective reactions.
• Material Science: A building block for specialty polymers and advanced materials requiring specific molecular geometry.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Heptan-3-One, (1R,4S)-
CAS No.	134003-02-4
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	(1R,4S)-2-Azabicyclo[2.2.1]heptan-3-one; (1R,4S)-3-Oxo-2-azabicyclo[2.2.1]heptane; (-)-2-Azabicyclo[2.2.1]heptan-3-one; (1R,4S)-3-Azabicyclo[2.2.1]heptan-2-one; L-2-Azabicyclo[2.2.1]heptan-3-one; (1R,4S)-Bicyclic lactam; (1R,4S)-3-Oxo-2-azabicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Every batch of (1R,4S)-2-Azabicyclo[2.2.1]heptan-3-one is produced under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.