Description

2-Amino-8,9-Dimethoxy-1,3,4,6,11,11A-Hexahydro-2H-Benzo[B]Quinolizine CAS NO 133899-10-2 is a complex heterocyclic amine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique structural framework, which is essential for synthesizing specific alkaloid-based active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical sectors engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex alkaloid-derived drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Organic Synthesis Research: Valuable precursor for academic and industrial research exploring novel heterocyclic chemistry and reaction pathways.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals requiring a sophisticated benzoquinolizine backbone.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Biochemical Research: Potential tool compound for investigating biological pathways and receptor interactions due to its specific amine and methoxy functionalities.

Basic Information

Item	Details
Product Name	2-Amino-8,9-Dimethoxy-1,3,4,6,11,11A-Hexahydro-2H-Benzo[B]Quinolizine
CAS No.	133899-10-2
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	2-Amino-8,9-dimethoxy-1,3,4,6,11,11a-hexahydro-2H-benzo[b]quinolizine; 8,9-Dimethoxy-1,3,4,6,11,11a-hexahydro-2H-benzo[b]quinolizin-2-amine; 2-Amino-8,9-dimethoxyhexahydrobenzo[b]quinolizine; Benzo[b]quinolizine, 2-amino-8,9-dimethoxy-1,3,4,6,11,11a-hexahydro-; 133899-10-2
EINECS	Contact for details

Quality Control

Our 2-Amino-8,9-Dimethoxy-1,3,4,6,11,11A-Hexahydro-2H-Benzo[B]Quinolizine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.