Description

[(S)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Bis(2-Methylallyl)Ruthenium(II) is a highly specialized, chiral ruthenium complex designed for advanced asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex, single-enantiomer molecules.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing chiral intermediates in active pharmaceutical ingredients (APIs).
• Asymmetric C-H Activation: Enables direct, enantioselective functionalization of C-H bonds, streamlining synthetic routes for complex organic molecules.
• Asymmetric Allylic Substitution: Facilitates the formation of chiral carbon centers through nucleophilic attack on allylic substrates with high stereocontrol.
• Pharmaceutical Intermediate Synthesis: Key for constructing chiral building blocks for drugs targeting CNS disorders, cardiovascular diseases, and oncology.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new asymmetric transformations in process chemistry.

Basic Information

Product Name	[(S)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Bis(2-Methylallyl)Ruthenium(II)
CAS No.	133773-19-0
Molecular Formula	C54H48P2Ru
Molecular Weight	870.00 g/mol
Synonyms	(S)-BINAP-Ru(2-methylallyl)2; (S)-Ru(BINAP)(2-methylallyl)2; (S)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl bis(2-methylallyl)ruthenium; (S)-BINAP Ru(dimethallyl)2; Ruthenium, bis(2-methyl-2-propen-1-yl-kappaC)[(1,1'-binaphthalene)-2,2'-diyl]bis[diphenylphosphine-kappaP]-, (S)-; (S)-BINAP-Ru(η3-2-methylallyl)2; (S)-BINAP-Ru(dimethallyl)2
EINECS	Contact for details

Quality Control

Every batch of our [(S)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Bis(2-Methylallyl)Ruthenium(II) is synthesized and handled under strict inert atmosphere conditions to preserve its catalytic activity. We employ advanced analytical techniques including NMR (1H, 31P), HPLC, and elemental analysis to ensure high chemical purity and chiral integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and moisture-sensitive; all handling should be performed in a glovebox or using rigorous Schlenk-line techniques to prevent decomposition.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Elemental Analysis (C, H)	Within theoretical ± 0.4%
Solubility	Soluble in toluene, dichloromethane, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.