Description

2-Amino-1-(3,5-Difluorophenyl)Ethanol is a versatile chiral amino alcohol building block characterized by its difluorinated aromatic ring. This compound is of significant commercial importance as a key intermediate in the synthesis of advanced pharmaceutical active ingredients and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug classes.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides that leverage the difluorophenyl moiety for enhanced biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics, materials science, and advanced research applications.
• Academic and R&D: Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and the development of new chemical entities.

Basic Information

Product Name	2-Amino-1-(3,5-Difluorophenyl)Ethanol
CAS No.	133562-33-1
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	2-Amino-1-(3,5-difluorophenyl)ethanol; 1-(3,5-Difluorophenyl)-2-aminoethanol; 3,5-Difluoro-β-amino-phenethyl alcohol; (RS)-2-Amino-1-(3,5-difluorophenyl)ethanol; 2-Amino-2-(3,5-difluorophenyl)ethan-1-ol; α-Amino-3,5-difluorobenzeneethanol; Amino alcohol DFPE
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(3,5-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as required)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.