Description

2-Methyl-2-[(4-Phenylphenyl)Methylamino]Propane-1,3-Diol Hydrochloride is a high-purity organic compound with the CAS number 133550-81-9, serving as a key intermediate in advanced pharmaceutical synthesis. Its molecular structure makes it valuable for the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise stereochemistry and functional group manipulation. This product is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and life sciences sectors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Chemical Research & Development: Used as a versatile synthon in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in scale-up and pilot plant operations for the production of specialty fine chemicals.
• Academic Research: Serves as a reagent in university and institutional labs for investigating new organic reactions and synthetic methodologies.
• Bioconjugation Chemistry: Potential use in the development of linker molecules for antibody-drug conjugates (ADCs) and other targeted therapies.

Basic Information

Product Name	2-Methyl-2-[(4-Phenylphenyl)Methylamino]Propane-1,3-Diol Hydrochloride
CAS No.	133550-81-9
Molecular Formula	C18H24ClNO2
Molecular Weight	321.84 g/mol
Synonyms	2-Methyl-2-[(4-biphenylyl)methylamino]-1,3-propanediol hydrochloride; 1,3-Propanediol, 2-methyl-2-[[(1,1'-biphenyl)-4-ylmethyl]amino]-, hydrochloride; 2-Methyl-2-[(4-phenylbenzyl)amino]propane-1,3-diol hydrochloride; Biphenyl-4-ylmethyl-(2-methyl-1,3-dihydroxy-2-propyl)amine hydrochloride; (RS)-2-Methyl-2-[(4-phenylbenzyl)amino]propane-1,3-diol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-[(4-Phenylphenyl)Methylamino]Propane-1,3-Diol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.