Description

1H-Inden-1-Ol,2-Fluoro-2,3-Dihydro-,trans-(9Ci) is a high-purity fluorinated indanol derivative, a key chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific stereochemistry and fluorine atoms into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom and specific stereochemistry can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, particularly in fluorination and stereoselective synthesis protocols.

Basic Information

Product Name	1H-Inden-1-Ol,2-Fluoro-2,3-Dihydro-,trans-(9Ci)
CAS No.	133413-63-5
Molecular Formula	C9H9FO
Molecular Weight	152.16 g/mol
Synonyms	trans-2-Fluoro-2,3-dihydro-1H-inden-1-ol; (1R,2S)-2-Fluoro-2,3-dihydro-1H-inden-1-ol (enantiomer); (1S,2R)-2-Fluoro-2,3-dihydro-1H-inden-1-ol (enantiomer); 2-Fluoroindan-1-ol; Fluorinated Indanol; Chiral Fluorohydrin Building Block
EINECS	Contact for details

Quality Control

Our 1H-Inden-1-Ol,2-Fluoro-2,3-Dihydro-,trans-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and GC/HPLC for purity assessment, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.