Description

Endo-1-Azabicyclo[2.2.1]Heptane-3-Carboxylic Acid, Ethyl Ester is a high-value, nitrogen-containing bicyclic building block of significant interest in advanced organic synthesis. This compound is prized for its rigid, three-dimensional scaffold, which is instrumental in constructing complex molecular architectures with defined stereochemistry. It serves as a critical intermediate for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where a rigid, functionalized amine core is required for biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands used in asymmetric catalysis.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological systems and enzyme functions.
• Advanced Material Science: Acts as a monomer or functional additive in the research of specialty polymers with unique thermal or mechanical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in stereoselective synthesis and ring-forming reactions.

Basic Information

Product Name	Endo-1-Azabicyclo[2.2.1]Heptane-3-Carboxylic Acid, Ethyl Ester
CAS No.	133366-43-5
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Ethyl Endo-1-Azabicyclo[2.2.1]heptane-3-carboxylate; 3-Carbethoxyendonorborane; 1-Azabicyclo[2.2.1]heptane-3-carboxylic acid, ethyl ester, endo-; Ethyl 1-azabicyclo[2.2.1]heptane-3-carboxylate (endo-); Bicyclo[2.2.1]heptane-3-carboxylic acid, 1-aza-, ethyl ester, endo-; 3-(Ethoxycarbonyl)endonorborane; endo-Norborane ethyl ester
EINECS	Contact for details

Quality Control

Our Endo-1-Azabicyclo[2.2.1]Heptane-3-Carboxylic Acid, Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive analytical data, including chiral purity verification, to support your regulatory and development needs. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (endo- isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.