Description

Capsular Polysaccharide Type 7, Actinobacillus Pleuropneumoniae is a purified, high-molecular-weight carbohydrate antigen derived from the bacterial pathogen *Actinobacillus pleuropneumoniae*. This specific serotype 7 capsular polysaccharide is a critical component for the research, development, and quality control of veterinary vaccines and diagnostic assays. It is essential for immunologists, microbiologists, and biopharmaceutical manufacturers focused on combating porcine respiratory diseases. The material serves as a key reference standard and antigenic target for ensuring vaccine efficacy and diagnostic accuracy in the global animal health sector.

Application

• Veterinary Vaccine Development: As a key antigenic component in the formulation of subunit or conjugate vaccines against *Actinobacillus pleuropneumoniae* serotype 7.
• Immunological Research: For studying host-pathogen interactions, immune response mechanisms, and serotype-specific virulence in porcine pleuropneumonia.
• Diagnostic Assay Production: Used as a coating antigen or standard in ELISA, latex agglutination, and other serological tests to detect specific antibodies in animal sera.
• Quality Control & Potency Testing: Serves as a reference standard for the identity, purity, and potency testing of commercial vaccines and diagnostic kits.
• Antibody Production & Purification: Employed for the immunization of animals to generate polyclonal or monoclonal antibodies specific to the Type 7 capsular polysaccharide.
• Biochemical & Structural Analysis: For research into the polysaccharide's chemical structure, composition, and role in bacterial adhesion and immune evasion.

Basic Information

Product Name	Capsular Polysaccharide Type 7, Actinobacillus Pleuropneumoniae
CAS No.	133268-59-4
Molecular Formula	(C6H10O5)n (Polysaccharide, variable)
Molecular Weight	High molecular weight polymer (Contact for details)
Synonyms	APP Serotype 7 Capsular Polysaccharide; *Actinobacillus pleuropneumoniae* Type 7 CPS; *A. pleuropneumoniae* Serotype 7 Antigen; Polysaccharide Antigen Type 7; APP-7 Capsular Antigen; Bacterial Capsular Polysaccharide Serotype 7; Porcine Pleuropneumonia Polysaccharide Antigen
EINECS	Contact for details

Quality Control

Our Capsular Polysaccharide Type 7 is produced and tested under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot is characterized for identity, purity, and specific antigenic properties. Certificates of Analysis (COA) are provided, detailing specifications such as polysaccharide content, protein/nucleic acid impurities, and serological identity. We adhere to relevant quality guidelines suitable for research and bioprocessing applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For extended storage, consider under inert atmosphere or desiccant.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (Serology)	Positive for *A. pleuropneumoniae* Type 7
Identification (Chemical)	Consistent with polysaccharide (e.g., IR, NMR)
Polysaccharide Content	≥ 90% (by colorimetric assay)
Protein Content	≤ 1.0% (by Bradford or BCA assay)
Nucleic Acid Content	≤ 0.5% (by UV absorbance)
Moisture Content (Loss on Drying)	≤ 5.0%
Biological Activity (ELISA)	Reactive with specific antisera
Endotoxin Level	< 10 EU/mg (by LAL assay)
Sterility (for specific grades)	Sterile or Low Bioburden

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.