Description

3-Iodo-2-Methylbenzoic Acid is a high-purity halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of iodine and methyl groups on the aromatic ring, making it an excellent precursor for cross-coupling reactions and a versatile intermediate for creating complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystal materials.
• Cross-Coupling Reactions: An essential substrate in Suzuki-Miyaura, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Organic Ligand Preparation: Utilized for synthesizing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	3-Iodo-2-Methylbenzoic Acid
CAS No.	133232-56-1
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	2-Methyl-3-iodobenzoic Acid; 3-Iodo-o-toluic Acid; 3-Iodo-2-methylbenzoic acid; Benzoic acid, 3-iodo-2-methyl-; 2-Methyl-3-iodobenzoic acid; 3-Iodo-2-methyl-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Methylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.