Description

(3-Trifluoromethoxy-Phenyl)-Hydrazine Hydrochloride is a specialized aromatic hydrazine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique reactivity of the hydrazine moiety combined with the electron-withdrawing trifluoromethoxy substituent, enabling precise construction of heterocyclic scaffolds and functionalized aromatic systems. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, including potential kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced biological activity and metabolic stability.
• Heterocyclic Chemistry: Fundamental building block for constructing pyrazole, indazole, and other nitrogen-containing heterocycles via cyclization and condensation reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Derivatization: Acts as a reagent for the introduction of the (3-trifluoromethoxyphenyl)hydrazinyl group into target molecules for structure-activity relationship (SAR) studies.
• Analytical Reference Standard: Serves as a high-purity standard for quality control and analytical method development in chemical production.

Basic Information

Product Name	(3-Trifluoromethoxy-Phenyl)-Hydrazine Hydrochloride
CAS No.	133115-55-6
Molecular Formula	C7H8F3N2O·HCl
Molecular Weight	232.61 g/mol
Synonyms	1-(3-Trifluoromethoxyphenyl)hydrazine hydrochloride; 3-(Trifluoromethoxy)phenylhydrazine hydrochloride; m-Trifluoromethoxyphenylhydrazine hydrochloride; (3-Trifluoromethoxyphenyl)hydrazine HCl; [3-(Trifluoromethoxy)phenyl]hydrazine hydrochloride; 1-Hydrazinyl-3-(trifluoromethoxy)benzene hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Trifluoromethoxy-Phenyl)-Hydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to consistent quality and traceability supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.