Description

6-[2-(tert-Butoxycarbonyl)Hydrazinyl]Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected hydrazine moiety. This compound is critical for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and manufacturing facilities in the pharmaceutical, agrochemical, and fine chemical industries for constructing heterocyclic scaffolds and introducing functionalized pyridine units.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing nicotinic acid or hydrazine derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific pyridine-based structures.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis for constructing complex heterocycles and introducing protected functional groups.
• API Manufacturing: Employed in the scalable production of Active Pharmaceutical Ingredients where the tert-butoxycarbonyl (Boc) group provides orthogonal protection.
• Ligand and Catalyst Development: Potential use in the creation of specialized ligands for metal catalysis due to its nitrogen-rich coordination sites.

Basic Information

Product Name	6-[2-(tert-Butoxycarbonyl)Hydrazinyl]Nicotinic Acid
CAS No.	133081-25-1
Molecular Formula	C11H15N3O4
Molecular Weight	253.25 g/mol
Synonyms	6-Hydrazinylnicotinic acid tert-butyl carbazate; 6-(2-((tert-Butoxycarbonyl)hydrazinyl))nicotinic acid; 2-Pyridinecarboxylic acid, 6-[2-[(1,1-dimethylethoxy)carbonyl]hydrazinyl]-; Nicotinic acid, 6-[2-(tert-butoxycarbonyl)hydrazinyl]-; Boc-hydrazino nicotinic acid; 6-(N-Boc-hydrazino)nicotinic acid; 6-(2-(tert-Butoxycarbonyl)hydrazinyl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-[2-(tert-Butoxycarbonyl)Hydrazinyl]Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.