Description

1,3-Bis(Trifluoroacetyl)-2-(4-Nitro-3-Indolyl)-4-Imidazoline is a specialized heterocyclic organic compound featuring a unique trifluoroacetylated imidazoline core linked to a nitro-substituted indole moiety. This molecular architecture makes it a valuable advanced intermediate for the synthesis of complex pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with indole and imidazoline pharmacophores.
• Chemical Biology Probes: Serves as a precursor for creating labeled or tagged molecules used to study biological processes.
• High-Purity Reference Standard: Supplied to analytical and quality control laboratories for method development and compound identification.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Item	Detail
Product Name	1,3-Bis(Trifluoroacetyl)-2-(4-Nitro-3-Indolyl)-4-Imidazoline
CAS No.	133053-95-9
Molecular Formula	C₁₇H₈F₆N₄O₅
Molecular Weight	462.26 g/mol
Synonyms	2-(4-Nitro-1H-indol-3-yl)-1,3-bis(2,2,2-trifluoroacetyl)-4,5-dihydro-1H-imidazole; 1,3-Bis(2,2,2-trifluoroacetyl)-2-(4-nitro-1H-indol-3-yl)-4,5-dihydro-1H-imidazole; 2-(4-Nitro-3-indolyl)-1,3-bis(trifluoroacetyl)-4-imidazoline; 1,3-Bis(trifluoroacetyl)-2-(4-nitroindol-3-yl)-4-imidazoline; 4-Imidazoline, 1,3-bis(trifluoroacetyl)-2-(4-nitro-3-indolyl)-
EINECS	Contact for details

Quality Control

Our 1,3-Bis(Trifluoroacetyl)-2-(4-Nitro-3-Indolyl)-4-Imidazoline is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.