Description

2-Aziridinyl-1,4-Naphthoquinon-5-Yl 4-tert-Butylbenzenesulfonate is a specialized synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel, high-value chemical entities, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate complex quinone and aziridine motifs into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of experimental drug candidates, particularly those targeting specific enzyme inhibition or designed as bioreductive alkylating agents.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection, leveraging its reactive functional groups.
• Polymer Science: Acts as a cross-linking agent or functional monomer in the creation of specialty polymers with unique thermal or chemical properties.
• Bioconjugation Chemistry: Employed in research for labeling biomolecules (e.g., proteins, antibodies) due to its electrophilic character.
• Academic & Institutional R&D: Utilized in universities and research institutes for fundamental studies in organic reaction mechanisms and heterocyclic chemistry.
• Material Science: Investigated for use in creating organic electronic materials or photoactive compounds.

Basic Information

Product Name	2-Aziridinyl-1,4-Naphthoquinon-5-Yl 4-tert-Butylbenzenesulfonate
CAS No.	133042-00-9
Molecular Formula	C22H21NO5S
Molecular Weight	411.47 g/mol
Synonyms	5-(4-tert-Butylbenzenesulfonyloxy)-2-(aziridin-1-yl)-1,4-naphthoquinone; 2-(Aziridin-1-yl)-5-[(4-tert-butylphenyl)sulfonyl]oxy]-1,4-naphthalenedione; 1,4-Naphthoquinone, 2-aziridinyl-5-[(4-(1,1-dimethylethyl)phenyl)sulfonate]; 4-tert-Butylbenzenesulfonic Acid 2-Aziridinyl-1,4-dihydro-1,4-dioxo-5-naphthyl Ester; Aziridinylnaphthoquinone Sulfonate Ester; BQ-4-tert-BuSulfonate Derivative
EINECS	Contact for details

Quality Control

Our 2-Aziridinyl-1,4-Naphthoquinon-5-Yl 4-tert-Butylbenzenesulfonate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and moisture uptake. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.