Description

2-Chloro-4,5-Difluoro-3-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique halogenated and nitro-substituted benzoic acid structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the difluoro and nitro groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	2-Chloro-4,5-Difluoro-3-Nitrobenzoic Acid
CAS No.	132992-44-0
Molecular Formula	C7H2ClF2NO4
Molecular Weight	237.55 g/mol
Synonyms	Benzoic acid, 2-chloro-4,5-difluoro-3-nitro-; 3-Nitro-2-chloro-4,5-difluorobenzoic acid; 2-Chloro-4,5-difluoro-3-nitrobenzoic acid; 4,5-Difluoro-2-chloro-3-nitrobenzoic acid; 132992-44-0; 2-Chloro-4,5-difluoro-3-nitro-benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4,5-Difluoro-3-Nitrobenzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring compliance with your research or production specifications. Our commitment to consistent quality and supply reliability supports your critical development timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.