Description

1-(6-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Piperazine is a high-value, multi-functional heterocyclic building block and intermediate of significant importance in advanced organic synthesis. Its core value lies in the unique combination of a piperazine ring with a halogenated pyridine moiety, enabling precise molecular modifications for creating novel compounds with targeted properties. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, antiviral agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a linker or scaffold in the design of molecular probes and biochemical tools.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	1-(6-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Piperazine
CAS No.	132834-56-1
Molecular Formula	C10H9ClF3N3
Molecular Weight	263.65 g/mol
Synonyms	1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]piperazine; 6-Chloro-5-(trifluoromethyl)-2-piperazin-1-ylpyridine; 2-Chloro-6-piperazinyl-3-(trifluoromethyl)pyridine; 1-(6-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine; Piperazine, 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 132834-56-1
EINECS	Contact for details

Quality Control

Our production of 1-(6-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Piperazine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with global regulatory frameworks, including REACH and cGMP where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its fluoride/strong alkali chemical property classification, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.