Description

Benzo(G)Chrysene-11,12-Dihydrodiol-13,14-Epoxide is a high-purity, synthetically derived polycyclic aromatic hydrocarbon (PAH) metabolite of significant research interest. This compound matters as a critical reference standard and biochemical tool for studying the metabolic activation pathways and carcinogenic mechanisms of complex PAHs. It is primarily needed by research institutions, analytical laboratories, and pharmaceutical companies engaged in environmental toxicology, cancer research, and analytical method development.

Application

• Environmental Toxicology Research: Used as a definitive analytical standard for quantifying and characterizing PAH metabolites in environmental samples, soil, and air particulate matter.
• Biochemical and Carcinogenesis Studies: Serves as a key intermediate in laboratory investigations of DNA adduct formation and the metabolic pathways leading to the mutagenicity of benzo[g]chrysene.
• Analytical Method Development & Validation: Essential for calibrating advanced analytical instruments like HPLC, GC-MS, and LC-MS/MS in methods designed to detect trace-level PAH derivatives.
• Pharmaceutical Research: Employed in studies focused on understanding chemical carcinogenesis, aiding in the development of potential chemopreventive agents.
• Reference Material Production: Supplied to certified reference material (CRM) producers for creating accredited standards used in regulatory testing and quality assurance programs.
• Academic Research & Teaching: Utilized in university laboratories for advanced coursework and postgraduate research in organic chemistry, toxicology, and environmental science.

Basic Information

Product Name	Benzo(G)Chrysene-11,12-Dihydrodiol-13,14-Epoxide
CAS No.	132832-27-0
Molecular Formula	C₂₂H₁₄O₃
Molecular Weight	326.35 g/mol
Synonyms	Benzo[g]chrysene-11,12-dihydrodiol-13,14-epoxide; 13,14-Epoxy-11,12-dihydroxy-11,12-dihydrobenzo[g]chrysene; Benzo[g]chrysene diol epoxide; B[g]C DE; (+/-)-Benzo[g]chrysene 11,12-diol 13,14-epoxide; anti-Benzo[g]chrysene-11,12-dihydrodiol-13,14-epoxide; PAH Metabolite (B[g]C)
EINECS	Contact for details

Quality Control

Our Benzo(G)Chrysene-11,12-Dihydrodiol-13,14-Epoxide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, NMR and IR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and ensure long-term stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in DMSO, Acetone; Slightly soluble in Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.