Description

4-(2-Methoxyphenyl)-2-Carboxy-3-Pyrrolidineacetic Acid is a high-purity pyrrolidine derivative with significant synthetic utility. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its multifunctional carboxylic acid groups. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Employed as a precursor for constructing complex molecular architectures requiring high enantiomeric purity in medicinal chemistry.
• Ligand and Catalyst Development: Used in the synthesis of novel chiral ligands and organocatalysts for stereoselective transformations.
• Peptidomimetic Research: Serves as a constrained, non-natural amino acid analog in the design of peptide-like compounds with enhanced metabolic stability.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploratory synthesis in organic chemistry.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	4-(2-Methoxyphenyl)-2-Carboxy-3-Pyrrolidineacetic Acid
CAS No.	132785-33-2
Molecular Formula	C14H17NO5
Molecular Weight	279.29 g/mol
Synonyms	2-Carboxy-4-(2-methoxyphenyl)-3-pyrrolidineacetic Acid; 4-(2-Methoxyphenyl)-2-carboxy-3-pyrrolidineacetic Acid; 3-Pyrrolidineacetic Acid, 4-(2-methoxyphenyl)-2-carboxy-; (2S,3S,4S)-4-(2-Methoxyphenyl)-2-carboxy-3-pyrrolidineacetic Acid (for specific stereoisomer); 132785-33-2; o-Methoxyphenyl pyrrolidine diacid derivative
EINECS	Contact for details

Quality Control

Our 4-(2-Methoxyphenyl)-2-Carboxy-3-Pyrrolidineacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.