Description

Benzo[C]Chrysene-trans-9,10-Dihydrodiol is a high-purity, polycyclic aromatic hydrocarbon (PAH) metabolite of significant interest in research and analytical chemistry. This compound serves as a critical standard and intermediate for studying metabolic pathways, environmental fate, and the biological activity of PAHs. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, environmental science, and toxicology sectors who require precise and reliable reference materials for their analytical and investigative work.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of HPLC, GC-MS, and LC-MS systems in environmental and biological monitoring.
• Metabolic Studies: Serves as a key intermediate or metabolite in research focused on the biotransformation and carcinogenicity of benzo[c]chrysene and related PAHs.
• Toxicological Research: Employed in in vitro and in vivo studies to investigate DNA adduct formation, genotoxicity, and cellular response mechanisms.
• Environmental Analysis: Acts as a standard for quantifying PAH metabolites in complex matrices such as soil, water, and air particulate samples.
• Pharmaceutical Impurity Profiling: Used in method development and validation for the identification and quantification of potential genotoxic impurities in drug substances.
• Biochemical Reagent: Utilized in enzymatic assays to study the activity of dihydrodiol dehydrogenases and other metabolizing enzymes.

Basic Information

Product Name	Benzo[C]Chrysene-trans-9,10-Dihydrodiol
CAS No.	132769-74-5
Molecular Formula	C₂₂H₁₆O₂
Molecular Weight	312.36 g/mol
Synonyms	trans-9,10-Dihydroxy-9,10-dihydrobenzo[c]chrysene; Benzo[c]chrysene 9,10-dihydrodiol; 9,10-Dihydrobenzo[c]chrysene-9,10-diol; BcC 9,10-dihydrodiol; PAH Metabolite Standard; Benzo(c)chrysene-dihydrodiol
EINECS	Contact for details

Quality Control

Every batch of Benzo[C]Chrysene-trans-9,10-Dihydrodiol is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and/or MS), and related substance profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or Certificate of Analysis. Keep the container in a cool, dry, and well-ventilated place. For long-term storage, consider storing under an inert atmosphere at lower temperatures (-20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.