Description

Phenol, 3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- CAS NO 132681-13-1 is a protected phenol derivative where the hydroxyl group is masked by a tetrahydropyranyl (THP) ether group, a versatile protecting group in synthetic organic chemistry. This compound is critical for multi-step synthesis, allowing chemists to selectively manipulate other functional sites on the phenol ring without affecting the hydroxyl group. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key protected intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing phenol functionalities that require selective deprotection.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides where the phenol moiety is a core structural element.
• Fine Chemical Production: Acts as a crucial precursor for synthesizing complex dyes, pigments, and specialty polymers that require controlled reactivity.
• Academic & R&D Laboratories: A valuable reagent for method development and exploratory synthesis in medicinal chemistry and total synthesis projects.
• Material Science Research: Employed in the creation of novel monomers and ligands for catalysts or advanced polymeric materials.

Basic Information

Product Name	Phenol, 3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-
CAS No.	132681-13-1
Molecular Formula	C11H14O3
Molecular Weight	194.23 g/mol
Synonyms	3-(Tetrahydro-2H-pyran-2-yloxy)phenol; 3-(THP-O)phenol; 3-Hydroxyphenyl tetrahydropyranyl ether; 3-(Oxan-2-yloxy)phenol; Phenol, m-(tetrahydro-2H-pyran-2-yloxy)-; 3-Phenol THP ether; m-(Tetrahydropyran-2-yloxy)phenol; 1,3-Benzenediol, mono(tetrahydro-2H-pyran-2-yl) ether
EINECS	Contact for details

Quality Control

Our Phenol, 3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards required for GMP and ISO-guided production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.