Description

4-Chloro-8-Cyanoquinoline is a versatile and high-value quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive quinoline core.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis Building Block: Enables various cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations for creating complex heterocyclic compounds.
• Ligand and Catalyst Development: Utilized in the design of novel chelating ligands for catalysis and metal complexation studies.

Basic Information

Product Name	4-Chloro-8-Cyanoquinoline
CAS No.	132664-45-0
Molecular Formula	C10H5ClN2
Molecular Weight	188.61 g/mol
Synonyms	8-Cyano-4-chloroquinoline; 4-Chloro-8-quinolinecarbonitrile; 4-Chloroquinoline-8-carbonitrile; Quinoline, 4-chloro-8-cyano-; 132664-45-0; 4-Chloro-8-cyano-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Cyanoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.