Description

4-Chloro-8-Methoxy-Quinoline-2-Carboxylic Acid Methyl Ester is a high-purity, versatile quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in developing advanced crop protection agents and pesticides due to its bioactive quinoline core.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and organic electronic materials.
• Chemical Synthesis: A versatile building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Academic & Industrial R&D: Employed in discovery chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-Chloro-8-Methoxy-Quinoline-2-Carboxylic Acid Methyl Ester
CAS No.	132634-27-6
Molecular Formula	C₁₂H₁₀ClNO₃
Molecular Weight	251.66 g/mol
Synonyms	Methyl 4-Chloro-8-methoxyquinoline-2-carboxylate; 4-Chloro-8-methoxy-2-quinolinecarboxylic acid methyl ester; 2-Quinolinecarboxylic acid, 4-chloro-8-methoxy-, methyl ester; 132634-27-6; 4-Chloro-8-methoxyquinoline-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-8-Methoxy-Quinoline-2-Carboxylic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.