Description

1-Hydroxypyrene-D9 is a high-purity, deuterium-labeled internal standard critical for advanced analytical quantification. This compound is essential for ensuring accuracy and reliability in sensitive mass spectrometry-based analyses, where isotopic dilution is required. It is primarily needed by analytical laboratories, environmental testing facilities, and pharmaceutical R&D departments engaged in trace-level detection of polycyclic aromatic hydrocarbon (PAH) metabolites.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the precise quantification of 1-hydroxypyrene in biological and environmental samples via liquid chromatography-tandem mass spectrometry.
• Biomonitoring Studies: Critical for human exposure assessment to PAHs, particularly in urine analysis for occupational health and environmental epidemiology.
• Environmental Analysis: Employed in the testing of soil, water, and air particulate matter for PAH metabolite contamination.
• Method Development & Validation: Serves as a key reference material for developing and validating robust analytical methods in compliance with regulatory guidelines.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetic (DMPK) studies involving compounds with pyrene-like structures.
• Quality Control Reference: Acts as a certified reference material in laboratory quality control and proficiency testing programs.

Basic Information

Product Name	1-Hydroxypyrene-D9
CAS No.	132603-37-3
Molecular Formula	C16H D9 O
Molecular Weight	217.28 g/mol (approx.)
Synonyms	1-Hydroxypyrene-d9; 1-Pyrenol-d9; [D9]-1-Hydroxypyrene; 1-Hydroxypyrene (Deuterated); Pyren-1-ol-d9; 1-HP-d9; Deuterated 1-Hydroxypyrene Internal Standard
EINECS	Contact for details

Quality Control

Our 1-Hydroxypyrene-D9 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) detailing batch-specific results for identity, purity, and isotopic purity are provided. We support compliance with relevant standards for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as indicated on the label or CoA. For long-term storage, keep the container in a cool, dry, well-ventilated place. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D9)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.