Description

3-(3-Hydroxy-Prop-1-Ynyl)-Benzoic Acid is a versatile aromatic carboxylic acid derivative featuring both a terminal alkyne and a hydroxyl group, making it a valuable bifunctional building block in organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture for advanced material and pharmaceutical development. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and polymer science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptor sites.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive functional groups.
• Ligand and Catalyst Development: The alkyne and carboxylic acid moieties make it suitable for constructing complex ligands for metal-organic frameworks (MOFs) and homogeneous catalysts.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties, such as high-performance resins and coatings.
• Click Chemistry: The terminal alkyne group is ideal for Huisgen 1,3-dipolar cycloaddition reactions, facilitating rapid and modular synthesis of diverse compound libraries.
• Bioconjugation: Employed in the modification of biomolecules for diagnostic and therapeutic applications, enabling the attachment of probes or drugs.

Basic Information

Product Name	3-(3-Hydroxy-Prop-1-Ynyl)-Benzoic Acid
CAS No.	132545-15-4
Molecular Formula	C10H8O3
Molecular Weight	176.17 g/mol
Synonyms	3-(3-Hydroxyprop-1-yn-1-yl)benzoic acid; 3-(3-Hydroxy-1-propynyl)benzoic Acid; Benzoic acid, 3-(3-hydroxy-1-propynyl)-; m-(3-Hydroxy-1-propynyl)benzoic Acid; 3-Carboxyphenylpropiolic alcohol; 3-(3-Hydroxypropynyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-(3-Hydroxy-Prop-1-Ynyl)-Benzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory needs, we can support documentation requirements for cGMP, ISO, or other quality management systems upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.