Description

2-Deoxy-2-Fluoroinositol 1,4,5-Trisphosphate is a fluorinated analog of the critical second messenger inositol 1,4,5-trisphosphate (IP3). This compound matters as a potent and selective research tool for probing intracellular calcium signaling pathways and IP3 receptor pharmacology. It is primarily needed by researchers in pharmaceutical discovery, biochemistry, and cell biology for investigating cellular communication, neurological disorders, and cardiac function.

Application

• Biochemical Research: As a high-affinity ligand for studying IP3 receptor binding, activation, and modulation.
• Cell Signaling Studies: To investigate calcium (Ca²⁺) release from endoplasmic reticulum stores in various cell types.
• Neurological Research: For exploring the role of IP3-mediated signaling in synaptic plasticity, neural development, and neurodegenerative diseases.
• Cardiovascular Research: Used in studies of cardiac muscle contraction and the regulation of heart cell function.
• Drug Discovery: Serves as a reference standard and tool compound in screening assays for novel therapeutics targeting GPCR and calcium signaling pathways.
• Enzymology: As a substrate or inhibitor for enzymes involved in inositol phosphate metabolism, such as phosphatases and kinases.

Basic Information

Product Name	2-Deoxy-2-Fluoroinositol 1,4,5-Trisphosphate
CAS No.	132489-75-9
Molecular Formula	C6H12FO15P3
Molecular Weight	508.06 g/mol
Synonyms	2-Deoxy-2-fluoro-myo-inositol 1,4,5-trisphosphate; 2-Fluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate; 2-F-IP3; Fluorinated IP3 analog; 2-Fluoro-D-myo-inositol 1,4,5-trisphosphate; myo-Inositol, 2-deoxy-2-fluoro-, 1,4,5-tris(dihydrogen phosphate); IP3 Fluoro Analog
EINECS	Contact for details

Quality Control

Our 2-Deoxy-2-Fluoroinositol 1,4,5-Trisphosphate is produced under strict quality management to ensure batch-to-batch consistency for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by weight)
Water Content	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.