Description

5-(1,1-Dimethylethyl)-2-[(1S,3R)-3-Hydroxycyclohexyl]Phenol is a high-purity, chiral phenolic compound of significant interest in advanced organic synthesis. Its value lies in its unique stereochemistry and functional groups, making it a versatile chiral building block and intermediate for complex molecule construction. This product is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and hormone modulators.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective reactions to introduce specific three-dimensional configurations into target molecules.
• Ligand and Catalyst Development: Serves as a core structure for designing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals, agrochemicals, and advanced materials.
• Academic and Industrial R&D: A critical reagent for methodological studies in organic chemistry and process development in pilot-scale facilities.

Basic Information

Item	Detail
Product Name	5-(1,1-Dimethylethyl)-2-[(1S,3R)-3-Hydroxycyclohexyl]Phenol
CAS No.	132296-16-3
Molecular Formula	C16H24O2
Molecular Weight	248.36 g/mol
Synonyms	(1S,3R)-3-(4-tert-Butyl-2-hydroxyphenyl)cyclohexanol; 4-tert-Butyl-2-[(1S,3R)-3-hydroxycyclohexyl]phenol; (1S,3R)-3-Hydroxy-4'-tert-butylbiphenyl-2-ol (cyclohexyl analog); Chiral BHT derivative; CAS 132296-16-3; (1S,3R)-Isomer of 3-(4-tert-butyl-2-hydroxyphenyl)cyclohexanol
EINECS	Contact for details

Quality Control

Our production of 5-(1,1-Dimethylethyl)-2-[(1S,3R)-3-Hydroxycyclohexyl]Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm identity, enantiomeric excess (ee), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.