Description

4-Trimethylaminopyridine is a versatile and highly effective catalyst and organic synthesis intermediate. This compound is particularly valued for its role in accelerating acylation and esterification reactions, offering superior performance compared to traditional catalysts like DMAP (4-Dimethylaminopyridine). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to improve reaction yields and efficiency in complex synthetic pathways.

Application

• Pharmaceutical Synthesis: A key catalyst and building block in the production of active pharmaceutical ingredients (APIs), particularly for acylation and esterification steps.
• Agrochemical Manufacturing: Used in the synthesis of advanced pesticides, herbicides, and plant growth regulators.
• Polymer Chemistry: Acts as a catalyst in the production of specialty polymers, including polyesters and polycarbonates.
• Fine Chemical Production: Facilitates the synthesis of dyes, pigments, and other complex organic molecules.
• Academic & Industrial Research: A valuable reagent for methodological development and scale-up studies in organic chemistry laboratories.
• Peptide Synthesis: Employed as an efficient catalyst for coupling reactions in solid-phase peptide synthesis.

Basic Information

Product Name	4-Trimethylaminopyridine
CAS No.	132151-83-8
Molecular Formula	C8H12N2
Molecular Weight	136.20 g/mol
Synonyms	4-(N,N,N-Trimethylamino)pyridine; 4-(Trimethylammonio)pyridine; TMAP; N,N,N-Trimethyl-4-pyridinamine; 4-Pyridinamine, N,N,N-trimethyl-; 4-Trimethylammoniumpyridine
EINECS	Contact for details

Quality Control

Our 4-Trimethylaminopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.