Description

6-Iodo-Quinazoline-2,4-Diamine is a high-purity, halogenated quinazoline derivative, a critical building block in advanced organic synthesis. Its value lies in its versatile diamine functionality and iodine substituent, enabling precise molecular construction for complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing targeted kinase inhibitors and novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other targeted cancer therapeutics.
• Agrochemical Research: Used in the development of novel fungicides and herbicides, leveraging the quinazoline core's bioactivity.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study enzyme function and signal transduction pathways.
• Material Science: Potential building block for advanced organic electronic materials and metal-organic frameworks (MOFs) due to its nitrogen-rich, planar structure.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for the preparation of bespoke, high-value specialty chemicals.

Basic Information

Product Name	6-Iodo-Quinazoline-2,4-Diamine
CAS No.	132131-20-5
Molecular Formula	C8H7IN4
Molecular Weight	302.07 g/mol
Synonyms	2,4-Diamino-6-iodoquinazoline; 6-Iodo-2,4-quinazolinediamine; 6-Iodoquinazoline-2,4-diyldiamine; 132131-20-5; Quinazoline, 2,4-diamino-6-iodo-; 6-Iodo-2,4-diaminoquinazoline
EINECS	Contact for details

Quality Control

Our 6-Iodo-Quinazoline-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.