Description

1,4-Dioxaspiro[2.2]Pentane,2,5-Bis(1-Methylethyl)-,[2Alpha,3Bta(R*)]-(9Ci) is a specialized spirocyclic compound with the CAS number 132014-24-5, valued as a versatile chiral building block and intermediate in advanced organic synthesis. Its unique stereochemistry and functionalized dioxolane ring system make it a critical precursor for constructing complex molecular architectures. This high-purity intermediate is essential for research and development in the pharmaceutical and fine chemical industries, where precise stereocontrol is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Ligand and Catalyst Development: Used in the preparation of novel chiral ligands and organocatalysts for stereoselective transformations.
• Fine Chemical Production: Serves as a precursor for high-value specialty chemicals, agrochemicals, and flavors & fragrances.
• Material Science Research: Investigated as a monomer or cross-linking agent for the development of novel polymers with specific stereochemical properties.
• Academic & Industrial R&D: A valuable tool for chemists in discovery chemistry and process development for complex molecule synthesis.

Basic Information

Product Name	1,4-Dioxaspiro[2.2]Pentane,2,5-Bis(1-Methylethyl)-,[2Alpha,3Bta(R*)]-(9Ci)
CAS No.	132014-24-5
Molecular Formula	C11H20O2
Molecular Weight	184.28 g/mol
Synonyms	2,5-Diisopropyl-1,4-dioxaspiro[2.2]pentane; (2R,3R)-2,5-Diisopropyl-1,4-dioxaspiro[2.2]pentane; 1,4-Dioxaspiro[2.2]pentane, 2,5-bis(1-methylethyl)-, (2α,3β)-rel-; Spiro[2.2]pentane-1,4-diol, 2,5-diisopropyl-, cyclic acetal; Chiral dioxolane spiro compound; 132014-24-5; (rel)-(2R,3R)-2,5-Diisopropyl-1,4-dioxaspiro[2.2]pentane
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxaspiro[2.2]Pentane,2,5-Bis(1-Methylethyl)-,[2Alpha,3Bta(R*)]-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested against rigorous in-house specifications, with a focus on chiral purity (enantiomeric excess) and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.