Description

3-Nitro- Dl-Phenylalanine, Methyl Ester, Monohydrochloride is a chemically modified amino acid derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in providing a functionalized phenylalanine scaffold with a nitro group and ester-protected carboxylic acid, enabling diverse chemical transformations. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science, particularly for creating novel peptide mimetics and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, enzyme inhibitors, and peptide-based therapeutics.
• Agrochemical Research: Used in developing advanced pesticides and herbicides by providing a functionalized aromatic amino acid core.
• Peptide Chemistry: Serves as a protected and modified amino acid residue for solid-phase peptide synthesis (SPPS) and peptide library construction.
• Biochemical Probe Development: Utilized in creating labeled analogs and activity-based probes for studying enzyme mechanisms and biological pathways.
• Chiral Resolution Studies: Acts as a model compound for developing and testing new methods of enantiomeric separation due to its DL (racemic) nature.
• Academic & Industrial R&D: Fundamental building block in organic synthesis for constructing complex molecules with nitro-aromatic functionalities.

Basic Information

Product Name	3-Nitro- Dl-Phenylalanine, Methyl Ester, Monohydrochloride
CAS No.	131980-27-3
Molecular Formula	C10H12N2O4 • HCl
Molecular Weight	260.67 g/mol (Free base) / 297.13 g/mol (HCl salt)
Synonyms	DL-3-Nitrophenylalanine methyl ester hydrochloride; Methyl 3-nitro-DL-phenylalaninate hydrochloride; (±)-3-Nitro-phenylalanine methyl ester HCl; 3-NO2-Phe-OMe • HCl; Methyl (RS)-2-amino-3-(3-nitrophenyl)propanoate hydrochloride; 3-Nitro-DL-phenylalanine methyl ester monohydrochloride; (RS)-2-Amino-3-(3-nitrophenyl)propionic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Nitro- Dl-Phenylalanine, Methyl Ester, Monohydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.