Description

3-Deoxy-β-Manno-2-Octulosonic Acid Thioglycoside is a specialized thioglycoside derivative of a key bacterial lipopolysaccharide (LPS) component. This compound is a critical building block and synthetic intermediate for advanced research in glycochemistry and immunology. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel vaccines, diagnostics, and glycoconjugate-based therapeutics targeting bacterial infections.

Application

• Glycoconjugate Vaccine Development: As a key intermediate in the synthesis of bacterial oligosaccharide antigens for conjugation to carrier proteins.
• Immunological Research: For studying host-pathogen interactions, immune response mechanisms, and the role of specific LPS epitopes.
• Synthetic Chemistry: Serving as a versatile thioglycosyl donor in the stereoselective synthesis of complex oligosaccharides and glycoconjugates.
• Diagnostic Reagent Production: Used in the development of specific antibodies, ELISA kits, and other detection tools for bacterial serotyping.
• Biochemical Tool Compound: For enzymatic studies and probing the activity of glycosyltransferases and other carbohydrate-active enzymes.
• Pharmaceutical Intermediates: In the research and development pipeline for novel anti-infective and immunomodulatory agents.

Basic Information

Product Name	3-Deoxy-β-Manno-2-Octulosonic Acid Thioglycoside
CAS No.	131853-21-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	KDO Thioglycoside; 3-Deoxy-D-manno-oct-2-ulosonic Acid Thioglycoside; Thioglycosyl KDO; 2-Keto-3-deoxyoctonate Thioglycoside; KDO-SR; Bacterial LPS Thioglycoside Intermediate; Glycosyl Thio Derivative of KDO; 3-Deoxy-β-D-manno-oct-2-ulopyranosonic Acid Thioglycoside
EINECS	Contact for details

Quality Control

Our 3-Deoxy-β-Manno-2-Octulosonic Acid Thioglycoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under an inert atmosphere after opening and allowed to equilibrate to room temperature before use to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.