Description

(S)-3-Amino-1-Benzylpyrrolidine Dihydrochloride is a high-purity chiral amine salt, serving as a critical building block in advanced organic synthesis. Its enantiopure structure makes it an indispensable intermediate for the development of active pharmaceutical ingredients (APIs) and sophisticated chemical entities. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel compounds with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Catalysis Ligand Precursor: Used to develop chiral ligands and organocatalysts for enantioselective synthesis.
• Agrochemical Research: Employed in the development of novel, stereospecific pesticides and herbicides.
• Chemical Biology & Proteomics: Acts as a scaffold or modifying agent in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Peptidomimetics Development: Incorporated into the backbone of peptide analogs to enhance stability and biological activity.
• Academic & Industrial R&D: Serves as a standard or starting material for methodological development in synthetic organic chemistry.

Basic Information

Product Name	(S)-3-Amino-1-Benzylpyrrolidine Dihydrochloride
CAS No.	131852-54-5
Molecular Formula	C11H18Cl2N2
Molecular Weight	249.18 g/mol
Synonyms	(S)-1-Benzyl-3-aminopyrrolidine dihydrochloride; (S)-3-Amino-1-benzylpyrrolidinium chloride; (S)-1-Benzyl-3-pyrrolidinamine dihydrochloride; (S)-3-Amino-1-(phenylmethyl)pyrrolidine dihydrochloride; (S)-ABP dihydrochloride; (S)-1-Benzyl-3-aminopyrrolidine hydrochloride (1:2); (S)-3-Amino-1-benzyl-pyrrolidine HCl
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-1-Benzylpyrrolidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.