Description

Dirhodium (Ii) Tetrakis(Methyl 2-Pyrrolidone-5(R)-Carboxylate)Acetonitrile/2-Propanol Complex is a highly specialized chiral dirhodium(II) carboxylate catalyst, distinguished by its unique pyrrolidone-based ligand framework. This compound is engineered to provide exceptional stereocontrol and catalytic efficiency in demanding asymmetric transformations. It is a critical reagent for research and development chemists in the pharmaceutical and fine chemical industries, where precise enantioselective synthesis is paramount for creating active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Asymmetric C-H Functionalization: A premier catalyst for enantioselective insertion reactions into C-H bonds, enabling streamlined synthesis of complex chiral molecules.
• Pharmaceutical Intermediate Synthesis: Essential for the construction of stereogenic centers in the development of novel APIs, including antiviral, anticancer, and central nervous system (CNS) agents.
• Cyclopropanation and Cycloaddition Reactions: Facilitates highly enantioselective [2+1] and [3+2] cycloadditions to form strained carbocyclic and heterocyclic ring systems.
• Methodology Development in Academic & Industrial R&D: A tool of choice for developing new catalytic asymmetric methodologies in organic synthesis laboratories.
• Fine Chemical and Agrochemical Production: Used in the pilot and commercial-scale synthesis of enantiomerically pure flavors, fragrances, and advanced agrochemicals.
• Material Science Precursors: Employed in the synthesis of chiral ligands and metal-organic frameworks (MOFs) with specific asymmetric properties.

Basic Information

Item	Details
Product Name	Dirhodium (Ii) Tetrakis(Methyl 2-Pyrrolidone-5(R)-Carboxylate)Acetonitrile/2-Propanol Complex
CAS No.	131796-58-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dirhodium(II) tetrakis[methyl (5R)-2-oxo-5-pyrrolidinecarboxylate] acetonitrile/isopropanol complex; Rh2(5R-MEPY)4•CH3CN/2-Propanol; Dirhodium(II) (R)-methyl 2-pyrrolidone-5-carboxylate complex; Chiral dirhodium(II) carboxylate catalyst; Rh2(R-MPYC)4; Asymmetric dirhodium catalyst; Dirhodium tetracarboxylate complex
EINECS	Contact for details

Quality Control

Every batch of our Dirhodium (Ii) Tetrakis(Methyl 2-Pyrrolidone-5(R)-Carboxylate)Acetonitrile/2-Propanol Complex is manufactured and tested under strict quality management systems. We ensure high catalytic activity and enantiomeric purity through advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, solvent content, and performance characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade its catalytic performance.

Specification

Item	Specification
Appearance	Green to blue-green crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Rhodium Content	Contact for details
Solvent Content (Residual Solvents)	Meets ICH guidelines
Specific Rotation	Contact for details
Catalytic Activity	Performance tested in model asymmetric reaction

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.