Description

(1R,2S)-(+)-2-Aminocyclohex-3-Enecarboxylic Acid Hydrochloride is a high-purity chiral building block of significant interest in advanced organic synthesis. Its value lies in its rigid, functionalized cyclohexene scaffold, which serves as a key intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Peptidomimetics and Conformationally Restricted Peptides: The constrained cyclohexene ring structure is incorporated to mimic peptide turns and stabilize specific bioactive conformations.
• Academic and R&D Laboratories: Employed in methodological studies and the exploration of new synthetic routes involving amino acid derivatives.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Item	Details
Product Name	(1R,2S)-(+)-2-Aminocyclohex-3-Enecarboxylic Acid Hydrochloride
CAS No.	131783-54-5
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	(1R,2S)-2-Amino-3-cyclohexene-1-carboxylic acid hydrochloride; (1R,2S)-(+)-2-Amino-1,2,3,4-tetrahydrobenzoic acid hydrochloride; (1R,2S)-2-Aminocyclohex-3-ene-1-carboxylic acid HCl; cis-2-Aminocyclohex-3-ene-1-carboxylic acid hydrochloride; (1R,2S)-ACHC HCl; (1R,2S)-2-Amino-cyclohex-3-enecarboxylic acid hydrochloride; (1R,2S)-2-Acchc hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2S)-(+)-2-Aminocyclohex-3-Enecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, Chiral HPLC) are provided to guarantee consistent quality, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.