Description

2-Chloro-6-Fluoro-3-Methylquinoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated quinoline structure makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Serves as a core building block for developing new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient quinoline core.
• Ligand and Catalyst Preparation: Employed in the synthesis of complex ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Fluorescent Probe Development: Acts as a precursor for creating sensitive fluorescent markers and sensors used in biochemical assays and diagnostics.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-6-Fluoro-3-Methylquinoline
CAS No.	131610-11-2
Molecular Formula	C₁₀H₇ClFN
Molecular Weight	195.62 g/mol
Synonyms	2-Chloro-6-fluoro-3-methylquinoline; 3-Methyl-2-chloro-6-fluoroquinoline; 6-Fluoro-2-chloro-3-methylquinoline; Quinoline, 2-chloro-6-fluoro-3-methyl-; 131610-11-2; 2-Chloro-6-fluoro-3-methyl-quinoline; 6-Fluoro-2-chloro-3-methyl-quinoline
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Fluoro-3-Methylquinoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.