Description

3-Cyclobutene-1,2-Dione,3-Ethoxy-4-[[1-(Hydroxymethyl)Propyl]Amino]-,(R)-(9Ci) is a specialized chiral intermediate featuring a cyclobutenedione core, which is a valuable scaffold in synthetic organic chemistry. This compound matters for its role in the synthesis of complex molecules, particularly in pharmaceutical research where its defined stereochemistry and functional groups enable precise structural modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in projects targeting central nervous system (CNS) or metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that require a chiral, functionalized cyclobutane derivative.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or optical properties.
• Academic & Institutional Research: Employed in methodological studies and the exploration of new cycloaddition or annulation reactions in organic chemistry.
• Fine Chemical Synthesis: Intermediate for producing other high-value, complex specialty chemicals for various industrial applications.

Basic Information

Product Name	3-Cyclobutene-1,2-Dione,3-Ethoxy-4-[[1-(Hydroxymethyl)Propyl]Amino]-,(R)-(9Ci)
CAS No.	131588-96-0
Molecular Formula	C10H15NO4
Molecular Weight	213.23 g/mol
Synonyms	(R)-3-Ethoxy-4-[(1-hydroxymethylpropyl)amino]cyclobut-3-ene-1,2-dione; 3-Ethoxy-4-[[1-(hydroxymethyl)propyl]amino]-3-cyclobutene-1,2-dione, (R)-; 4-[(1-Hydroxymethyl-propyl)amino]-3-ethoxy-cyclobut-3-ene-1,2-dione; (R)-3-Ethoxy-4-((1-(hydroxymethyl)propyl)amino)cyclobut-3-ene-1,2-dione; 131588-96-0; (R)-enantiomer of 3-Ethoxy-4-[(1-hydroxymethylpropyl)amino]cyclobutenedione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 3-Cyclobutene-1,2-Dione,3-Ethoxy-4-[[1-(Hydroxymethyl)Propyl]Amino]-,(R)-(9Ci) is characterized and tested to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) containing detailed analytical results from techniques such as HPLC, NMR, and chiral analysis are available upon request. We adhere to cGMP principles for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.