Description

Win 55,212-2 Mesylate is a potent and selective synthetic cannabinoid receptor agonist, widely recognized as a key pharmacological research tool. Its primary value lies in its high affinity and specificity for cannabinoid receptors, making it indispensable for studying the endocannabinoid system's role in various physiological and pathological processes. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and academic sectors focused on neuroscience, pain management, and metabolic disorder research.

Application

• Neuroscience Research: Used as a standard agonist to investigate cannabinoid receptor (CB1 and CB2) signaling, neuronal excitability, and synaptic plasticity.
• Pharmacological Studies: Serves as a critical reference compound for in vitro and in vivo assays to evaluate the potency and efficacy of novel cannabinoid ligands.
• Drug Discovery & Development: Employed in high-throughput screening and target validation for conditions like chronic pain, inflammation, anxiety, and appetite regulation.
• Biochemical Assays: Utilized in receptor binding studies, functional assays (e.g., cAMP accumulation, GTPγS binding), and enzyme activity tests related to the endocannabinoid system.
• Academic & Institutional Research: A fundamental tool for university and government laboratories exploring the therapeutic potential and mechanisms of cannabinoid-based therapies.
• Reference Standard: Can be used as a certified reference material (CRM) for analytical method development and quality control in related pharmaceutical manufacturing.

Basic Information

Product Name	Win 55,212-2 Mesylate
CAS No.	131543-23-2
Molecular Formula	C₂₆H₂₈N₂O₃S
Molecular Weight	448.58 g/mol
Synonyms	WIN 55,212-2; WIN 55212-2; (R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone mesylate; WIN55,212-2 mesylate salt; WIN-55,212-2 mesylate; (R)-(+)-WIN 55,212-2 mesylate
EINECS	Contact for details

Quality Control

Every batch of Win 55,212-2 Mesylate is manufactured under strict quality management protocols. We provide comprehensive analytical documentation to support research integrity. Our standard quality commitment includes HPLC purity ≥98% (area percentage), with identity confirmed by spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results for purity, impurities, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.