Description

6-(2,2,2-Trifluoroethoxy)-1,3-Benzothiazol-2-Amine is a specialized benzothiazole derivative featuring a trifluoroethoxy substituent, a key structural motif valued in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine-containing group can significantly modulate biological activity and physicochemical properties. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoroethoxy group can improve lipophilicity and environmental stability.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for catalysts or components for organic light-emitting diodes (OLEDs).
• Biochemical Probe Development: Serves as a scaffold for creating fluorescent dyes or molecular probes used in diagnostic assays and biomedical imaging.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	6-(2,2,2-Trifluoroethoxy)-1,3-Benzothiazol-2-Amine
CAS No.	131395-08-9
Molecular Formula	C9H7F3N2OS
Molecular Weight	248.23 g/mol
Synonyms	2-Amino-6-(2,2,2-trifluoroethoxy)benzothiazole; 6-(2,2,2-Trifluoroethoxy)-2-benzothiazolamine; 2-Benzothiazolamine, 6-(2,2,2-trifluoroethoxy)-; 131395-08-9; 6-(Trifluoroethoxy)benzothiazol-2-amine; 6-(2,2,2-Trifluoroethoxy)-1,3-benzothiazol-2-ylamine; 2-Amino-6-(trifluoroethoxy)benzothiazole
EINECS	Contact for details

Quality Control

Our 6-(2,2,2-Trifluoroethoxy)-1,3-Benzothiazol-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.