Description

2-((S)-4,5-Dihydro-4-Isopropyloxazol-2-Yl)Phenol ,>95%(Ee>95%) is a high-purity, enantiomerically enriched chiral oxazoline derivative, serving as a critical building block and ligand in asymmetric synthesis. Its value lies in providing exceptional stereochemical control, enabling the production of optically active intermediates for advanced pharmaceuticals and agrochemicals. This compound is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries who require reliable, high-quality chiral auxiliaries to develop novel active ingredients.

Application

• Asymmetric Catalysis: Employed as a chiral ligand for transition metal catalysts in enantioselective C-C bond formation, hydrogenation, and other key transformations.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for optimal activity and environmental safety.
• Fine Chemical Production: Acts as a versatile building block for creating complex, high-value specialty chemicals with defined stereocenters.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and for exploring new routes in synthetic chemistry.
• Ligand Library Development: Used in the creation of diverse ligand libraries for high-throughput screening in catalyst discovery programs.

Basic Information

Product Name	2-((S)-4,5-Dihydro-4-Isopropyloxazol-2-Yl)Phenol ,>95%(Ee>95%)
CAS No.	131380-91-1
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	(S)-2-(4,5-Dihydro-4-(1-methylethyl)-2-oxazolyl)phenol; (S)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol; (S)-2-(4,5-Dihydro-4-isopropyl-2-oxazolyl)phenol; Phenol, 2-[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-; (S)-4-Isopropyl-2-(2-hydroxyphenyl)-4,5-dihydrooxazole; Chiral Oxazoline Ligand; (S)-IPHOX ligand derivative
EINECS	Contact for details

Quality Control

Every batch of our 2-((S)-4,5-Dihydro-4-Isopropyloxazol-2-Yl)Phenol undergoes rigorous analytical testing to ensure it meets the high standards required for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chemical purity, enantiomeric excess (ee), and identity confirmation. Our quality management system is designed to support cGMP and ISO guidelines for traceability and consistency, ensuring reliable performance in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	> 95.0%
Enantiomeric Excess (Chiral HPLC)	> 95.0% ee
Melting Point	Contact for details
Loss on Drying	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.