Description

7,7-Dimethyl-1,4-dioxaspiro[4.5]decan-8-ol is a high-value spirocyclic ketal alcohol intermediate with significant synthetic utility. This compound matters for its role as a versatile chiral building block in the synthesis of complex organic molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily needed by R&D chemists and process development teams for applications in asymmetric synthesis, fragrance development, and the production of advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring spirocyclic or complex stereocenters.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective reactions.
• Fragrance & Flavor Chemistry: Serves as a building block for creating novel musk-like or woody odorants and flavor compounds due to its spirocyclic structure.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of natural products, agrochemicals, and other specialty chemicals.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and new reaction development.

Basic Information

Product Name	7,7-Dimethyl-1,4-dioxaspiro[4.5]decan-8-ol
CAS No.	131206-74-1
Molecular Formula	C11H20O3
Molecular Weight	200.27 g/mol
Synonyms	8-Hydroxy-7,7-dimethyl-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decan-8-ol, 7,7-dimethyl-; 7,7-Dimethyl-1,4-dioxaspiro[4.5]decan-8-ol; Spiro[1,3-dioxolane-2,1'-cyclohexan]-5-ol, 4,4-dimethyl-; 4,4-Dimethylspiro[1,3-dioxolane-2,1'-cyclohexan]-5-ol; (8-Hydroxy-7,7-dimethyl-1,4-dioxaspiro[4.5]decane)
EINECS	Contact for details

Quality Control

Our 7,7-Dimethyl-1,4-dioxaspiro[4.5]decan-8-ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (if applicable)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.