Description

3,5-Di-o-Benzyl-1,2-o-Isopropylidene-β-D-Arabinofuranose is a key protected sugar intermediate, specifically a benzylated and isopropylidenated derivative of D-arabinofuranose. This compound is critically important for its role as a versatile chiral building block in the stereoselective synthesis of complex nucleosides, carbohydrates, and other biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, modified oligonucleotides, and novel glycosylation methodologies.

Application

• Nucleoside & Nucleotide Synthesis: A crucial chiral precursor for the preparation of modified nucleoside analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry: Serves as a protected arabinofuranose donor in the synthesis of oligosaccharides, glycoconjugates, and complex natural products.
• Pharmaceutical Intermediates: Used in the research and development stages for creating active pharmaceutical ingredients (APIs) targeting viral infections.
• Glycosylation Reagents: Acts as a glycosyl donor or acceptor in stereocontrolled glycosylation reactions to form specific glycosidic linkages.
• Chemical Biology Probes: Employed in the synthesis of labeled sugars or probes for studying biological recognition and enzymatic processes.
• Process Development: Utilized in scaling up synthetic routes for pharmaceutical candidates requiring arabinose-based scaffolds.

Basic Information

Product Name	3,5-Di-o-Benzyl-1,2-o-Isopropylidene-β-D-Arabinofuranose
CAS No.	131139-02-1
Molecular Formula	C22H26O5
Molecular Weight	370.44 g/mol
Synonyms	1,2-O-Isopropylidene-3,5-di-O-benzyl-α-D-arabinofuranose; 3,5-Di-O-benzyl-1,2-O-isopropylidene-α-D-arabinofuranose; 1,2-O-Isopropylidene-3,5-di-O-benzyl-D-arabinofuranose; 3,5-Di-O-benzyl-1,2-O-(1-methylethylidene)-α-D-arabinofuranose; D-Arabinofuranose, 3,5-di-O-benzyl-1,2-O-(1-methylethylidene)-, (3a,5β)-; Protected D-Arabinose Derivative
EINECS	Contact for details

Quality Control

Our 3,5-Di-o-Benzyl-1,2-o-Isopropylidene-β-D-Arabinofuranose is produced under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for demanding research and process development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom synthesis and purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.