Description

2-Hydroxy-2-Azaspiro[4.4]Nonane-1,3-Dione is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique spirocyclic and functionalized lactam structure, which serves as a critical precursor for developing novel pharmacologically active molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel spirocyclic compounds with potential biological activity.
• Drug Discovery Scaffold: Used in medicinal chemistry for building diverse compound libraries targeting various enzymes and receptors.
• Agrochemical Research: Serves as a precursor in the development of new active ingredients with herbicidal or insecticidal properties.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying biological pathways and protein function.
• Advanced Material Synthesis: Potential building block for specialty polymers or ligands in catalyst design due to its rigid, functionalized structure.

Basic Information

Product Name	2-Hydroxy-2-Azaspiro[4.4]Nonane-1,3-Dione
CAS No.	131042-60-9
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	2-Hydroxy-2-azaspiro[4.4]nonane-1,3-dione; 1,3-Dioxo-2-hydroxy-2-azaspiro[4.4]nonane; 2-Hydroxy-2-azaspiro[4.4]nonane-1,3-dione; 2-Hydroxy-2-azaspiro[4,4]nonane-1,3-dione; Spiro[4.4]nonane-1,3-dione, 2-hydroxy-2-aza-; 2-Azaspiro[4.4]nonane-1,3-dione, 2-hydroxy-; 131042-60-9
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-Azaspiro[4.4]Nonane-1,3-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.