Description

1-(Benzoyloxy)-3-Chloro-4-Hydroxyquinolinium Hydroxide, Inner Salt (6Ci) is a specialized quinoline derivative with a unique zwitterionic structure, making it a valuable synthetic intermediate and research chemical. Its core value lies in its ability to act as a precursor or building block for more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced organic materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, structurally defined intermediates for synthesis and screening.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development and research of new pesticides, herbicides, and fungicides where the quinoline scaffold is a core structural motif.
• Organic Synthesis Reagent: Acts as a versatile reagent or precursor in complex organic transformations, including cyclization and functional group transfer reactions, within academic and industrial R&D laboratories.
• Material Science Research: Investigated for the development of organic electronic materials, ligands for metal complexes, or specialty dyes due to its conjugated quinoline system and modifiable functional groups.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for method development, quality control, and regulatory testing in pharmaceutical and chemical manufacturing.

Basic Information

Product Name	1-(Benzoyloxy)-3-Chloro-4-Hydroxyquinolinium Hydroxide, Inner Salt (6Ci)
CAS No.	130986-77-5
Molecular Formula	C₁₆H₁₀ClNO₃
Molecular Weight	299.71 g/mol
Synonyms	3-Chloro-4-hydroxy-1-(benzoyloxy)quinolinium hydroxide inner salt; 1-Benzoyloxy-3-chloro-4-hydroxyquinolinium hydroxide inner salt; Quinolinium, 1-(benzoyloxy)-3-chloro-4-hydroxy-, hydroxide, inner salt; 6CI Index Name; 3-Chloro-4-hydroxyquinolin-1-ium-1-olate benzoate (tautomeric form)
EINECS	Contact for details

Quality Control

Our production of 1-(Benzoyloxy)-3-Chloro-4-Hydroxyquinolinium Hydroxide, Inner Salt (6Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications can be customized to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handle and store under an inert atmosphere if specified for your grade to ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.