Description

2-(1-Piperazinyl)-Quinoline is a versatile heterocyclic compound featuring a quinoline core linked to a piperazine moiety, a structural motif of significant interest in advanced chemical synthesis. This molecular architecture makes it a valuable pharmacophore and key synthetic intermediate for the development of novel active compounds. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents and specialized materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a ligand or precursor in the synthesis of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probe: Employed in research as a scaffold for developing enzyme inhibitors or receptor modulators to study biological pathways.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic chemistry and medicinal chemistry for constructing complex N-heterocycles.

Basic Information

Product Name	2-(1-Piperazinyl)-Quinoline
CAS No.	130895-61-3
Molecular Formula	C₁₃H₁₅N₃
Molecular Weight	213.28 g/mol
Synonyms	2-(Piperazin-1-yl)quinoline; 1-(Quinolin-2-yl)piperazine; Quinolin-2-yl-piperazine; 2-Quinolylpiperazine; 2-Piperazinylquinoline; 130895-61-3; 2-(1-Piperazinyl)quinoline
EINECS	Contact for details

Quality Control

Every batch of 2-(1-Piperazinyl)-Quinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.