Description

Sipatrigine CAS NO 130800-90-7 is a high-purity pharmaceutical intermediate and research chemical of significant interest in neuropharmacology. Its primary value lies in its role as a potent neuroprotective agent and sodium channel blocker, making it a critical compound for advanced research and development. This product is essential for pharmaceutical companies, academic research institutions, and contract research organizations (CROs) focused on developing novel therapeutics for neurological conditions, stroke, and pain management.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced neuroprotective drug candidates.
• Neurological Research: Used in preclinical studies to investigate mechanisms of neuroprotection and sodium channel modulation.
• Stroke Therapy Development: Employed in R&D for compounds aimed at reducing ischemic brain injury.
• Analytical Reference Standard: Serves as a high-purity standard for quality control and analytical method development in pharmaceutical labs.
• Life Science Research: Utilized in biochemical assays to study cellular responses to excitotoxicity and calcium overload.
• Contract Manufacturing: Supplied to CDMOs for the production of specialized, small-batch active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Sipatrigine
CAS No.	130800-90-7
Molecular Formula	C15H17N3O2S
Molecular Weight	303.38 g/mol
Synonyms	BW 619C89; (2,4-Dichlorophenyl)[(E)-2-(phenylsulfonyl)ethenyl]sulfone; 2,4-Dichloro-β-[(phenylsulfonyl)styryl] sulfone; BW-619C89; BW619C89; (E)-1-(2,4-Dichlorophenyl)-2-(phenylsulfonyl)ethene
EINECS	Contact for details

Quality Control

Every batch of Sipatrigine is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and pharmaceutical development. Comprehensive testing, including identity confirmation, purity assay, and impurity profiling, is performed. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.